Optimize your purification workflows with KNAUER Preparative HPLC Systems, designed for high-throughput compound isolation in research, production, and scale-up environments. Built with German precision, these systems offer exceptional scalability, robustness, and customization for applications in pharmaceuticals, natural products, biotechnology, and chemical synthesis.

KNAUER’s preparative systems support flexible flow rates and a wide range of column sizes, making them ideal for purifying milligram to gram quantities of substances. The systems are modular, allowing users to configure pumps, detectors, fraction collectors, and software to suit individual purification needs — from simple separations to complex multi-compound purification.

Key Features / Highlights

• Modular and scalable: Customizable for lab, pilot, or production scales.
• High throughput: Suitable for continuous and batch mode operation.
• Automation support: For fraction collection, solvent recycling, and more.
• Wide range of flow rates: From a few mL/min to several L/min.

Applications/Industries

1. Pharmaceutical Industry

• Purification of active pharmaceutical ingredients (APIs)
• Isolation of drug candidates from synthesis or fermentation processes
• Removal of impurities, byproducts, or enantiomers
• Scale-up from analytical R&D to production-scale purification

2. Natural Product Extraction

• Purification of plant extracts such as alkaloids, flavonoids, cannabinoids, etc.
• Isolation of bioactive compounds from herbs, marine organisms, or microbes
• Used in traditional medicine research and nutraceutical production

3. Biotechnology & Life Sciences

• Purification of peptides, proteins, oligonucleotides, and other biomolecules
• Downstream processing of fermentation products
• Preparative purification for structural biology studies

4. Chemical and Fine Chemical Industry

• Purification of specialty chemicals, intermediates, and fine chemicals
• Synthesis verification and isolation of desired products

5. Food and Beverage Industry

• Isolation of natural flavors, colorants, vitamins, or preservatives
• Used in quality control and ingredient refinement

6. Chiral Separations

• Preparative separation of enantiomers (e.g., in chiral drug development)
• Often used with chiral columns for racemic mixture resolution

7. Custom Synthesis & Contract Manufacturing

• Utilized by CROs/CMOs for compound isolation and contract purification services
• Ideal for pilot-scale or batch-scale production

Link to the Original Product Page: https://www.knauer.net/preparative-hplc?gad_campaignid=21211046527