KNAUER – GPC/SEC Systems

AZURA® SEC systems—featuring Compact, Lab, Semi‑Prep, and GPC Cleanup variants—offer tailored solutions for analytical, semi-preparative, and automated sample cleanup workflows. With ultra-low pulsation pumps, high-precision detectors, and intuitive chromatography software, you’ll experience efficient, high-throughput performance and simplified method development.

Product Description

Achieve precise molecular-size separation and purification with KNAUER’s AZURA® GPC/SEC systems, designed for cutting-edge research and industrial applications. Whether you’re analyzing polymers, biomolecules, or environmental samples, these systems deliver exceptional reproducibility and scalability—all backed by German engineering excellence.

AZURA® SEC systems—featuring Compact, Lab, Semi‑Prep, and GPC Cleanup variants—offer tailored solutions for analytical, semi-preparative, and automated sample cleanup workflows. With ultra-low pulsation pumps, high-precision detectors, and intuitive chromatography software, you’ll experience efficient, high-throughput performance and simplified method development.

Key Features / Highlights

  • Multiple system configurations: Compact, Lab, Semi‑Prep & Cleanup
  • High flow precision with ultra-low pulsation for reproducible results
  • Automated fraction collection and sample cleanup capabilities
  • Compatible detectors: UV/VIS, Refractive Index (RI), ELSD, DAD
  • Fully modular platforms to match lab needs
  • Supported by ClarityChrom® and PurityChrom® software

Applications/Industries
1. Synthetic Polymer Analysis

  • Molecular weight determination (Mn, Mw, Mz)
  • Polydispersity index (PDI) calculation
  • Used for analyzing plastics, resins, adhesives, and paints
  • QC and R&D in polymer manufacturing and formulation

2. Biopolymer and Protein Characterization

  • Size-based separation of:
    • Proteins
    • Polysaccharides (e.g., dextran, pullulan)
    • Peptides and nucleic acids
  • Aggregation studies (e.g., monomer vs. dimer vs. oligomer content in biologics)

3. Pharmaceutical and Biopharmaceutical Applications

  • Analysis of therapeutic proteins, antibodies, and vaccines
  • Monitoring aggregation or degradation in stability studies
  • Batch consistency in biosimilars or biopharmaceutical QC

4. Nanomaterials and Hydrodynamic Volume Studies

  • Used to estimate the size and distribution of nanoparticles or nanogels
  • Evaluation of polymer-drug conjugates, liposomes, and micelles

5. Food and Cosmetics

  • Characterization of polysaccharides, starches, or gums
  • Quality control of bioactive macromolecules in cosmetics and nutraceuticals

6. Academic & Industrial R&D

  • Fundamental research into polymer physics or protein folding
  • Used in materials science, biophysics, biochemistry, and chemical engineering

8. Quality Control (QC) and Process Monitoring

  • Batch-to-batch consistency verification
  • Polymer chain length and distribution control in production environments

Link to the Original Product Page: https://www.knauer.net/gpc/sec

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